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[Google Scholar] 71.Buse JB, Crowley M, Eriksson JW, Gislum M, Hertz CL, Kaiser M, et al

Only one in ten overweight or obese people currently use GLP-1 treatments, despite rising demand Half of the people who could benefit from GLP-1 weight-loss drugs may never get them, and some of the most powerful options may strip away more muscle than rivals, according to Reuters

Patients with lower genetic GLP-1 receptor activity may benefit from tirzepatide (which targets both GLP-1 and GIP receptors) rather than semaglutide alone

Understanding your genetic context can support a more informed conversation with your provider about mental health monitoring intensity, dosing strategy, and whether compounded semaglutide or tirzepatide formulations from PlexusDx's 503A partners might enable more gradual titration if mental health stability is a priority

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Eli Lilly plans to apply for FDA approval for retatrutide later this year, STAT reported