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Horowitz, H

[DOI] [PubMed] [Google Scholar] 76.Zhou W, et al

Metabolic modulation of the right ventricle and pulmonary circulation in pulmonary arterial hypertension: an interventional study using a Glucagon-like-peptide-1 (GLP-1) agonist

By activating both GIP and GLP-1 receptors, Mounjaro enhances insulin secretion in a glucose-dependent manner, suppresses glucagon release, slows gastric emptying, and reduces appetiteall of which contribute to improved glycaemic control and weight loss

If you live in one of the seven mandate states and have a Gold or Platinum plan, you have a 35% to 40% chance of approval after prior authorization, based on 2025 Centene claims data published in the Journal of Managed Care & Specialty Pharmacy (Thompson et al., 2025)

Additionally, no study to date has shown an increased risk of cancer recurrence or progression in patients utilizing these medications, providing clinicians with the reassurance needed to consider these drugs for patients struggling with severe metabolic dysfunction