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GLP-1 receptor agonists such as semaglutide (Ozempic, Wegovy), liraglutide (Victoza), and tirzepatide (Mounjaro, Zepbound) have dramatically improved treatment options for Type 2 diabetes and obesity

GLP-1 research tablet provides 25 x 7mg tablets of GLP-1 receptor agonist studied in preclinical models for incretin-pathway signaling, metabolic regulation, and energy-balance pathways

This review examines the biological mechanisms underlying GLP-1 RA therapy in MASLD/MASH, analyzes the mechanistic distinctions between mono-, dual-, and triple agonists, and synthesizes current clinical evidence supporting their utilization in individuals with this condition.