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Despite high price tags, the Wegovy and Zepbound obesity drugs are considered to be cost effective, because they help patients lose substantial weight that, in turn, reduces the risk of high blood pressure and diabetes, among other ailments, according to a preliminary analysis

Unlike semaglutide, which only targets GLP-1 receptors, tirzepatide is a dual agonist that targets GLP-1 and glucagon receptors

For mild to moderate pain, acetaminophen at recommended doses remains a first-line option for patients using GLP-1 medications

GLP-1 medications can make fat loss easier for many people

Diabetes Obes Metab 2019;21:499508

Aim for steady fluids through the day, and consider salted broth or a sugar-free electrolyte mix during longer fasting windows