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For some women, oral progesterone can slow gut motility, which may compound GI effects already seen with GLP-1s

NICE recommends considering surgical options for people with BMI 40 kg/m (or 35 kg/m with comorbidities)

Alternatives and Substitutes Is cost, access, or side effects making Mounjaro or Ozempic challenging

This rapid expansion of pharmacologic options is due, at least in part, to a better understanding of the pathophysiology of T2DM

Additionally, diabetes-related emotional distress and depression symptom severity have been identified as risk factors for medication non-adherence in T2DM [136, 137]