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Description
People with prediabetes tend to see similar improvements in A1c when taking either semaglutide or liraglutide
95% CI 0.270.92)

67,68 Still, the presence of GLP-1 RA-specific psychiatric adverse events that may also be related to drug intolerance requires the development of a strategy to overcome this barrier for the better implementation of GLP-1RA therapy

When exposed to a hyperglycemic milieu, the GIPR was found to downregulate in a study of pancreatic islet cells (59) and the patients with T2DM might express a small amount of GIPR or defective GIPR (60, 61)
doi: 10.1016/j.biopha.2020.110708, PMID: [DOI] [PubMed] [Google Scholar] 9

Dulaglutide reduces binge episodes in type 2 diabetic patients with binge eating disorder: A pilot study