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Large randomized clinical trials have consistently demonstrated that these agents not only improve glycemic control but also significantly reduce rates of cardiovascular death, heart failure hospitalization, and progression of chronic kidney disease [4,5,6]

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Aumenta o gasto energtico

But energy balance has two parts

doi: 10.1093/eurheartj/ehz486 [DOI] [PubMed] [Google Scholar] 13

But combining them may still cause some uncomfortable effects
