lilly glp 1 agonist is now pharma's top revenue company. It just got FDA approval for an oral GLP-1, but Wall Street isn't celebrating Aleniglipron: An Oral, Small Molecule

Anaesth Rep

Phase 3 TRIUMPH trials underway

Diagnosis of Diabetic Gastroparesis Diabetic gastroparesis is diagnosed by the presence of upper GI symptoms suggestive of delayed gastric emptying in a diabetic patient, exclusion of mechanical obstruction that could cause upper GI symptoms and the demonstration of delayed gastric emptying

doi:10.1007/s00125-017-4491-0

This systematic review evaluates the literature on the relationship between GLP-1 RA use and increased regurgitation and aspiration events to contextualize the existing, consensus-based guidelines put forth by the ASA in light of limited comparative evidence

This is often exacerbated by the "muscle-bone unit"as muscle mass is lost alongside fat, the bones lose the mechanical stimulus they need to stay dense