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Understanding the Physiology of GLP-1 GLP-1 is derived from the proglucagon gene from the L cells of the ileum and colon

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Probiotics and Type 1 Diabetes: An Interesting Connection A clinical trial on people with type 1 diabetes showed promising results using a probiotic blend ( Bifidobacterium longum , Lactobacillus bulgaricus , Streptococcus thermophilus ) over 12 weeks: Improved fasting blood sugar Reduced post-meal glucose spikes Better overnight stability And this was all without changing their insulin dose, suggesting that the gut flora itself helped balance blood sugar

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Some of these newer agents are based on modified human GLP-1 sequences rather than the lizard peptide, but they all owe their conceptual origins to the Gila monster discovery