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Glucagon-like peptide-1 increases heart rate by a direct action on the sinus node GLP-1 has direct chronotropic effects on the heart mediated by GLP-1 receptors in pacemaker cells of the sinus node, inducing changes in action potential morphology
The excess risk of acute pancreatitis was more pronounced during the early phase of follow-up (first 6 months)
PlexusDx explains the clinical reasons behind dose titration and how this approach maximizes weight loss while minimizing side effects
A phase 2 trial finds that combining semaglutide with bimagrumab leads to greater weight loss while preserving lean mass, highlighting the importance of body composition in obesity treatment.
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