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On the basis of these results, Ahn et al

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However, the study included a small number of participants and a shorter follow up time of only 48 weeks compared to other RCTs studying GLP-1 agonists

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Attempting to answer this question, the first surprising finding was that the PPG neurons do not express GLP1 receptors (Card et al., 2018

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Previous studies found that GLP-1RAs decreased alcohol use both in animal models [19-21] and in patients with alcohol use disorder [22]

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Wegovy contains semaglutide and targets the GLP-1 receptor only

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In contrast, those using Tirzepatide achieved higher monthly weight loss percentages: approximately 5.9% after 3 months, 10.1% after 6 months, and 15.3% after 12 months, surpassing the weight loss observed with semaglutide

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