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Diabet Med 2010

Contact your doctor or pharmacist if anything unusual occurs

Introduction Nonalcoholic fatty liver disease/nonalcoholic steatohepatitis (NAFLD/NASH) describes a group of diseases that are characterized by hepatic steatosis without the excessive intake of alcohol

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To view or add a comment, sign in Why N-acetylcysteine (NAC) is used in BOTH paracetamol toxicity and COPD Common link: GLUTATHIONE 1 Paracetamol (Acetaminophen) toxicity Paracetamol toxic metabolite NAPQI NAPQI is normally neutralized by glutathione Overdose glutathione depleted liver injury NAC replenishes glutathione detoxifies NAPQI prevents hepatic necrosis 2 COPD Chronic inflammation + oxidative stress Thick mucus worsens airflow obstruction NAC acts as: Antioxidant glutathione oxidative lung injury Mucolytic breaks disulfide bonds in mucus thinner secretions One-line takeaway NAC works by restoring glutathione In paracetamol toxicity detoxifies poison In COPD reduces oxidative stress + mucus viscosity #pharmacology #medicine #MedEd #medicine To view or add a comment, sign in Omeprazole is generally well tolerated, but it has a spectrum of adverse effects