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It mimics not just one but two hormones: GLP-1 and GIP

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The timeline from final phase 3 completion to approval generally spans 1224 months, provided the data is strong and regulatory review is smooth

Other putative mechanisms of action of GLP-1 RAs on vascular smooth muscles may include intracellular alterations in activities of protein kinase C, Rho-Kinase, myosin light chain kinase, as well as calcium handling, G-proteins, and ion channels (Xiong et al., 2019)

2023a, 2024a, 2024b)
