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Administration in Special Populations 14.1 Use in Elderly Patients 14.1.1 Dose Adjustments and Tolerability 14.1.2 Risk of Dehydration and Frailty 14.2 Use in Pregnant Women 14.2.1 Potential Risks to Fetus 14.2.2 Recommendations for Discontinuation 14.3 Use in Nursing Mothers 14.3.1 Drug Excretion in Breast Milk 14.3.2 Risk-Benefit Assessment 14.4 Use in Pediatric Population 14.4.1 Safety and Efficacy Data 14.4.2 Age Restrictions and Clinical Guidelines 15