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The FDA states that compounded drugs are "not reviewed by FDA prior to marketing and are not FDA-approved." What this means for consumers: When accessing compounded semaglutide or tirzepatide through telehealth platforms, you are receiving a medication that contains the same active ingredient as FDA-approved products but is prepared differently and has not undergone FDA approval as a finished product

In recent years, however, glucagon-like peptide-1 (GLP-1) receptor agonists have emerged as a cause of NAION, albeit evidence is mixed

Differences in efficacy among GLP-1 RAs belonging to the same class seem less significant
Thus, other drug delivery strategies were used to develop longer-acting GLP-1 RAs, as described below

Additionally, individuals with celiac disease have higher rates of other autoimmune conditions, including type 1 diabetes and autoimmune thyroid disease

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