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47 GLP-1RAs not only regulate cardiomyocyte activity, but also improve cardiac fibroblast performance

Common early signs include: Less hair in brush Less hair in drain Stronger strands Healthier scalp Reduced shedding Hair regrowth takes longer because follicles must complete a full cycle

With insulin resistance, common in people with excess adiposity, prediabetes, and type 2 diabetes, glucagon and insulin levels may be elevated
The FDA label carries a boxed warning regarding thyroid C-cell tumors observed in rodent studies, though the relevance to humans remains uncertain

Exception : IUDs and Nexplanon require temporary deferrals

Work with your healthcare team to taper metformin gradually if discontinuation is appropriate, ensuring glucose control remains stable throughout any transition
