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Mazdutide, a dual glucagon and GLP-1 agonist, is approved

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Common adverse effects include gastrointestinal symptoms such as nausea, vomiting, diarrhea, and constipation, which typically diminish over time

Clinical nutrition guidelines recommend that patients on weight loss therapy engage in regular physical activity and consume sufficient protein to help preserve muscle mass

The reactions reported ranged from relatively mild findings to less common but more significant skin reactions
