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In late-stage trials, the once-daily oral treatment helped overweight adults without diabetes lose 12.4% of their body weight over 72 weeks at the highest dose

Food and Drug Administration (FDA) for safety or effectiveness

10.1523/JNEUROSCI.0226-14.2014 [DOI] [PMC free article] [PubMed] [Google Scholar] Thomas, M

metabolic rate reductions during treatment are primarily attributable to weight loss itself rather than a specific drug effect

placebo Most effective in IBS-C & IBS-M patients Well-tolerated with no major side effects Phase 2a results ROSE-010s Effect on IBS Motility GI Transit Study (Camilleri et al.) Findings: Small intestine transit time increased Colonic transit time decreased Potential to improve IBS-C & IBS -M symptoms Whats Next

A moderate increase in protein consumption can help preserve muscle mass during weight loss