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Implications for employers : Employers should expect coverage of GLP-1 drugs for obesity to improve population health and employee productivity, but the return on investment from coverage is not likely to lead to lower medical costs now or in the future

Glucagon-like peptide-1 serum levels are associated with weight gain in patients treated with clozapine

Among these, osteoprotegerin (OPG), receptor activator for nuclear factor-B ligand (RANKL), and receptor activator for nuclear factor-B form a triangular relationship that regulates osteoclast differentiation, activation, and apoptosis

Obesity can lead to chronic, debilitating, and even life-threatening health issues such as diabetes, heart disease, and high blood pressure, so increased access to GLP-1 weight loss drugs could improve the long-term health, well-being, and outcome for millions of Americans

A prospective study

Cardiovascular and Kidney Outcomes and Mortality With Long-Acting Injectable and Oral Glucagon-Like Peptide 1 Receptor Agonists in Individuals With Type 2 Diabetes: A Systematic Review and Meta-analysis of Randomized Trials