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-1 : The global GLP-1 agonists market is expected to reach USD 170.75 billion in 2033 from USD 64.42 billion in 2025 at a CAGR of 13.0% during the forecast period

Previously, we identified a systemic dose of the GLP-1R agonist exendin-4 that selectively attenuated the reinstatement of cocaine-seeking behavior in rats 8 , effects mediated, in part, by activation of GLP-1Rs in the ventral tegmental area (VTA) 8

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Treatments were randomly allocated according to body weight

7,9 Although GLP1 RA-based therapies can play an important role in T2D and weight management, they should not be prescribed without a comprehensive lifestyle intervention