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GLP-1 Success Story GLP-1 agonists (also called GLP-1RAs), and related drugs like dual agonists of gastric inhibitory polypeptide (GIP)/GLP-1, have revolutionized obesity treatment by demonstrating significant and sustained weight loss in clinical trials and real-world use

Popular options include liraglutide, semaglutide, and exenatide

It actively increases energy expenditure at the metabolic level, a distinct mechanism that the GLP-1 and GIP arms cannot replicate

Individual results vary based on starting weight, adherence to treatment, lifestyle factors, and concurrent health conditions

Collins L et al

Hypertension: The Bridge Between Disease and Wellness Of all the non-obesity indications being built out around GLP-1s, hypertension deserves particular attention because it represents the most immediate, most commercially exploitable, and most reimbursable adjacent opportunity in the entire landscape