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Common side effects of semaglutide may include nausea, diarrhea, gastrointestinal disturbances, and constipation

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Synovial tissue and GLP-1R signalling Specialized cells, fibroblast-like synoviocytes and macrophage-like synoviocytes reside in the synovial membrane, composed of intimal and subintimal layers, which are responsible for notably producing hyaluronic acid and removing metabolites and matrix degradation debris, respectively [49]

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