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12 Oxidative stress, 13 mitochondrial dysfunction, 14 and endoplasmic reticulum (ER) stress 15 are all involved in NDs induced by brain IR

Furthermore, GLP-1 augments mitochondrial efficacy, as manifested by the ameliorated oxidative metabolism of muscle tissue

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ox-LDL: oxidized-LDL

The integration of adult-born neurons into the circuitry of the adult hippocampus suggests an important role for adult hippocampal neurogenesis in learning and memory