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According to market research company Mintel, in the US, 15% of adults who currently claim to be managing their weight are using GLP-1 medications

10.1016/j.exer.2021.108624 25 GuttenplanK

But to what extent can standalone GLP-1 interventions address overweight and obesity

People living with obesity due to POMC, PCSK1 or LEPR deficiency struggle with: Insatiable hunger, or hyperphagia, is not the same as regular hunger

Discoveries of GIP and GLP-1 The first incretin, GIP, was purified from canine intestinal extracts in the late 1960s (8) and initially named gastric inhibitory polypeptide (9) because the peptide inhibited gastrin-stimulated H + secretion (10)