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mGIPR-Ab treatment had no impact on fat mass (Extended Data Fig

These measurement changes often exceed what the raw weight loss would predict, because the shift in body composition means the body is not just smaller but shaped differently

critical revision of the manuscript for important intellectual content

Trial evidence supports significant reductions in body weight and waist circumference, both of which reflect fat loss

However, when both sygl-1 and lst-1 were removed, GLD-1(q361) protein increased dramatically in the distal germline ( Fig 6E ), with quantitation revealing a three-fold increase on average ( Fig 6F )

Photomicrographs were obtained with a Leica Aperio Versa slide scanner