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The dual effect is counterintuitive: Less acetaldehyde (liver-protective less toxic metabolite produced) Higher blood alcohol concentration (risky same drinks leave you more intoxicated) As principal investigator Wajahat Mehal, MD, professor of medicine at Yale, stated: "If these results are reproduced in humans, people using GLP-1 receptor agonists might be drinking an amount of alcohol that does not normally put them above the legal blood alcohol level, but because they are taking this drug, it does." Important caveat: This study was conducted in mice

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Compared to control, significant reductions in intracranial pressure were seen acutely at 2.5 h and 24 h, but also at 12 weeks [101]

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