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Lincoff et al., NEJM, 2023 (SELECT Trial) Targets a Key Pillar of Aging Semaglutide powerfully addresses metabolic dysfunction, one of the primary 'Hallmarks of Aging', helping to delay the onset of age-related diseases

Patients with type 2 diabetes, insulin resistance, or those looking to lose a significant amount of weight are often good candidates for the program

But in patients with pre-existing inflammatory bowel disease, the inflammatory cascade in the colon may be sensitized or amplified by GLP-1 activation, potentially triggering flares or worsening existing inflammation