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The study from Eli Lilly demonstrated a mean weight loss of 20.2% with tirzepatide (Zepbound) versus 13.7% with semaglutide (Wegovy) over a 72-week period

doi:10.1001/jama.294.22.2849

Continuous doseresponse relationships were modeled using generalized additive models (GAMs), with percent weight change as the dependent variable and weekly dose (mg) modeled as a smooth function

Phase 3 trials are specifically monitoring cardiovascular outcomes, and anyone with a pre-existing heart condition would need careful assessment before starting retatrutide assuming it gains approval

Unique Considerations for Thyroidectomy Patients Those whove had their thyroid removed need to watch out for special things when taking Ozempic

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