who makes the glp 1 drugs GLP-1 from Gray Market How GLP-1 medications are transforming

doi: 10.14309/ajg.0000000000002820

The underlying mechanism for increased heart rate remains to be elucidated but is hypothesized to be related to a direct effect at the sinus node and/or stimulation of the sympathetic nervous system, with this effect related to the duration of action of the respective GLP-1RAs (Lorenz et al

Li LC, Liang LM, Ji HY, Zhang C, Wang M, Liu HS

Mojca Jensterle has received lecture honoraria from Novo Nordisk, Eli Lilly, Pfizer, Amgen, Novartis and Sanofi, and is an advisory board member of Novo Nordisk, Eli Lilly, Amgen and Pfizer

GLP-1 medications may affect appetite and satiety pathways in some patients, but individual response varies

Baseline Demographics and Medication Profiles A total of 125 youth were included (median age 14.83 years), with 113 on metformin and 12 on GLP-1RA therapy