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Description
In a once-daily multiple ascending dose phase Ib clinical trial and a 41-day phase IIa trial in overweight and type 2 diabetic patients, general safety and tolerability of MEDI0382 were established, as well as placebo-corrected efficacy in reducing fasting blood glucose (1.7 mmol/L), post-prandial glucose excursions following a mixed meal test (22.6% AUC 04 h ), body weight (2.1 kg), and liver fat (19.6%) [7]

doi:10.3390/medicina59050985 Chandrakumar H, Khatun N, Gupta T, GrahamHill S, Zhyvotovska A, McFarlane SI

2025;23:715725.e3

This phenomenon underscores the need for clinicians to monitor nutritional status and gut microbiome biomarkers

2015;7(327): 327ra27
These help our doctors understand your unique metabolic profile and identify any underlying conditions that may benefit from GLP-1 treatment
