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Systematic monitoring of body weight, a key indicator of general health, was conducted every 48 h

[2] [3] Oligohidrosis and hyperthermia have been reported in association with topiramate use

Avg weight loss (72 weeks): ~20.9% (SURMOUNT-1) Side Effects by Dose Level Side effects are dose-dependent and most common during the first 12 weeks after each escalation

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Available evidence strongly suggests the opposite, that tirzepatide is actively supporting kidney health through multiple pathways including reduced inflammation, improved metabolic function, and decreased albuminuria