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It emerges from two converging threads: 1

The added 2.0 mg step gives clinicians an optional lever for patients who still need more glucose lowering

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Kannt A, Madsen AN, Kammermeier C, Elvert R, Klckener T, Bossart M, et al

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amino acid supplementation should be tested as part of weight loss programmes to mitigate loss of skeletal muscle. In new observational research presented at ENDO2025, Melanie Haines and colleagues found that adequate protein intake was predictive of less muscle loss in patients receiving semaglutide for obesity