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Short-acting GLP-1 receptor agonists primarily slow gastric emptying, and thus exert their main effect on postprandial blood glucose levels

Epub 2017 Feb 1

Regarding the vascular system, continuous infusion of the GLP-1 analog exendin-4 reduced monocyte adhesion to aortic endothelial cells, associated with a reduction in atherosclerotic lesion size in non-diabetic C57BL/6 and ApoE / mice

The mediation by GLP-1 receptors of glucagon-induced insulin secretion revisited in GLP-1 receptor knockout mice

Insulin breakthrough In the end the final breakthrough was made by a team at the University of Toronto (figure 6)

Additionally, oral small-molecule administration facilitates broader translational applications within experimental research