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Metabolism 69 , 148156 (2017)

Our slow titration approach addresses many of the nausea and GI complaints patients experienced on other programs

Primarily, semaglutide stimulates insulin secretion from pancreatic beta cells in a glucose-dependent manner, meaning it only triggers insulin release when blood glucose levels are elevated

In other words, if you are purchasing semaglutide from a distributor, your compliance program should be designed to ensure that your counterparty is meeting important regulatory requirements

However, any severe side effects should be reported to your doctor immediately

Diabetes Care 27:1335-1342, 2004