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Description
They minimize systemic inflammation by many mechanisms: direct suppression of pro-inflammatory cytokine synthesis (TNF-, IL-6, IL-1), augmentation of anti-inflammatory mediators (IL-10, adiponectin), and alteration of immune cell morphologies

Effectiveness and safety of the combination of sodium-glucose transport protein 2 inhibitors and glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes mellitus: a systematic review and meta-analysis of observational studies

The drugs are contraindicated in pregnant women due to risk of developmental abnormalities in the foetus

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Mechanisms of Cardiorenal Protection of Glucagon-Like Peptide-1 Receptor Agonists

2024 doi: 10.1177/15598276241280207
