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10.1016/j.ydbio.2008.11.024 Dev

What UAB Researchers Are Discovering The UAB article highlights that GLP-1 drugs dont just act in the gut they also have major effects in the brain

When patients achieve substantial weight loss through GLP-1 therapy, the biomechanical burden on these joints decreases proportionally
Additionally, GLP-1R activation results in transcription of genes involved in proliferation, neogenesis and apoptotic resistance in islet beta cells, expanding GLP-1s role from potentiating insulin secretion from islet beta cells to promoting their survival via translocation of pancreatic duodenal homeobox 1 (PDX-1) transcription factor to the nucleus 2,12,42

Retrieved from Sun, B., Willard, F.S., Feng, D., Alsina-Fernandez, J., Chen, Q., Vieth, M., Ho, J.D., Showalter, A.D., Stutsman, C., Ding, L., Suter, T.M., Dunbar, J.D., Carpenter, J.W., Mohammed, F.A., Aihara, E., Brown, R.A., Bueno, A.B., Emmerson, P.J., Moyers, J.S., Kobilka, T.S., Coghlan, M.P., Kobilka, B.K., Sloop, K.W
