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This article examines clinical safety data, GI mechanisms, and how genetic predispositions may influence medication tolerance in IBD patients see

We report that PPGNTS neurons encode satiation in mice, consistent with vagal gastrointestinal distension signalling

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The development of dual GIPRGLP1R coagonists that bind to either one or the other receptor (sequence-mixed dual agonists) has emerged as an innovative therapeutic strategy for obesity and type 2 diabetes

In late 2025, a seemingly narrow advertising dispute told a much bigger story about the GLP-1 market