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2019;4 doi: 10.1172/jci.insight.126742

Boubia B, Poupardin O, Barth M et al (2018) Design, Synthesis, and Evaluation of a Novel Series of Indole Sulfonamide Peroxisome Proliferator Activated Receptor (PPAR) alpha/gamma/delta Triple Activators: Discovery of Lanifibranor, a New Antifibrotic Clinical Candidate

Well-characterized mechanism including appetite suppression, glucose-dependent insulin secretion, and gastric emptying delay

Epidemiological data from the International Diabetes Federation (IDF) indicate that the global burden of diabetes affected approximately 463 million adults in 2019, with projections estimating a dramatic increase to 700 million cases by 2045 2
Ozempic suppresses appetite and slows digestion, which aids in weight loss
