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Chudleigh, R

Health Canada is likely to approve it closer to 2028

Dosing schedule per ALLUVI instructions: Weeks 14 (starting dose): 2.5 mg once weekly Weeks 58: 5 mg once weekly Weeks 913: 7.5 mg once weekly Weeks 14+: 10 mg once weekly Do not increase dose until hunger sensation returns

Due to appetite suppression and slowed digestion and gastric emptying, it is common for people on GLP-1 medications to eat fewer meals, and thus fewer calories, than they did before

It has also been noted that fat is preferentially lost from the trunk compared with the limbs in patients with IIH undergoing therapeutic weight loss resulting in significant reduction of ICP

Weight loss is typically 14 lbs in this window modest, primarily from reduced calorie intake rather than direct fat loss