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Therefore, the heterogeneities in cardiovascular medication, baseline characteristics, study population, and study design should be taken into consideration when comparing the results among these trials

The gastrointestinal side effect profile is similar but not identical

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What we do have are animal studies

Clinical Trials Demonstrating Reductions in Body Weight with GLP-1RAs Several clinical trials have reported that the effects described above resulted in larger reductions in body weight with GLP-1RA therapy compared with placebo in participants with obesity