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Hormonal Shifts & Appetite Regulation GLP-1 medications work by mimicking a hormone that helps regulate blood sugar, slow digestion, and suppress appetitebut this hormonal shift can also disrupt other body systems

Insulin deficiency or resistance interferes with glucose utilization, limiting energy availability for sperm motility ( 3 Mechanisms of spermatogenesis disorders 3.1 Mitochondria and oxidative stress Mitochondria play a pivotal role in regulating sperm function by modulating essential processes, including metabolism, signal transduction, energy production, and responses to oxidative stress

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However, Ozempic has shown significant results in weight loss in patients taking the medication for type 2 diabetes, leading to its increasing off-label use for weight management