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The MAC trial, a randomised crossover study from Loma Linda University, enrolled 35 overweight and obese adults with abdominal obesity and at least one additional cardiometabolic risk factor

The Lancet, 400(10366), 18691881

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Immediate management priorities include: Oral rehydration : Small, frequent sips of water or oral rehydration solutions (available from pharmacies) help replace lost fluids and electrolytes

Common injection sites include the upper arm and stomach