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A recent post hoc analysis of the SURPASS-1 through SURPASS-5 clinical trials further supports tirzepatide having a renal-protective action [96]
Start with the foundations: hydrate intentionally, prioritize proteins at meals, eat enough high-fiber carbs, and avoid skipping meals
These clinical trial figures may differ from real-world experience
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The hazard ratios (HRs) comparing tirzepatide to controls were 0.80 (95% CI, 0.571.11) for MACE-4, 0.90 (95% CI, 0.501.61) for cardiovascular death, and 0.80 (95% CI, 0.511.25) for all-cause death
Some individuals require 6 to 8 weeks at intermediate doses rather than the standard 4 weeks to achieve adequate tolerance
