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In a 12-month clinical trial involving 404 HIV-infected patients with excess abdominal fat, Tesamorelin (2 mg daily) significantly reduced visceral adipose tissue (VAT) compared to placebo

DO has served as a speaker for Boehringer Ingelheim, Eli Lilly and Novo Nordisk, and served on advisory boards for Roche Diagnostics and Sanofi

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Inhibition of DPP-IV elevates endogenous GLP concentrations, but DPP-IV also independently modulates inflammatory mediators, including stromal cell-derived factor 1 (SDF-1) and regulated upon activation, normal T cell expressed and presumably secreted (RANTES) (7981)
