how safe are glp-1 drugs weight-loss for older adults? The Clinical Application of GLP-1RAs

Kooijman, S

Geographic Availability Available in all 50 states (eligibility for compounded meds varies by state) Clinical Oversight and Safety Licensed providers review each case

GLP-1 receptor agonists (RA), such as Ozempic and Mounjaro, were initially designed to help manage blood sugar in type 2 diabetes

LIXIPARK, published in the New England Journal of Medicine in 2024, was the strongest result to date

It supports strength, mobility, insulin sensitivity, posture, balance, healthy aging, and long-term weight maintenance

In the second case, a 40-year-old woman with a history of depression reported worsening mood symptoms, including fatigue, cognitive slowing, and suicidal thoughts, approximately two months after beginning semaglutide for diabetes management