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At the pancreas, it potentiates glucose-stimulated insulin secretion while suppressing glucagon release, thereby lowering circulating glucose concentrations

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doi: 10.2147/CIA.S74042 7 WangXFLinXLiDYZhouRGreenbaumJChenYCet al

It features a naturally occurring, amidated C-terminal modification (-NH) that enhances its stability as well as biological function

CV Protection in the EMPA-REG OUTCOME trial: a thrifty substrate hypothesis

[DOI] [PMC free article] [PubMed] [Google Scholar] [52].Yang T, Zhang D