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[DOI] [PubMed] [Google Scholar] 26.Garza K., Aminpour E., Shah J., et al

These are aimed at giving patients more flexibility, reducing the cost burden and making adoption of these anti-obesity therapies easier

We have pulled one lever (weve lost the weight), but that means there is an equal and opposite reaction on the other side until the levers are balanced again (why did we gain it to begin with?)

So obviously I dug in deep to this literature

First, confirm the basics

In addition, exendin-4 injection enhanced calcium signals in DMH GLP-1R neurons in the pre-ingestive stage, and exendin-4-induced pre-ingestive satiation was mitigated by optogenetic inhibition of DMH GLP-1R neurons