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Description
New users of such drugs were defined as patients with a new (first) prescription and no prescription of the same drug class (GLP-1RA or BI) in the previous 12 months

While semaglutide does not directly cause leg cramps through its pharmacological mechanism, several indirect pathways related to its effects and the physiological changes during treatment may potentially contribute to muscle cramping in susceptible individuals

2024;13 doi: 10.18103/mra.v13i1.6236

Rising demand for these types of drugs, which mimic key hormones that tell us to feel full, have led to severe shortages of GLP-1s in recent months

If you're taking a GLP-1 and notice symptoms such as fatigue, dizziness, or dry mouth, dehydration may be one possible cause

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