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This triple mechanism distinguishes retatrutide from existing approved therapies such as semaglutide (a GLP-1 receptor agonist) or tirzepatide (a dual GIP/GLP-1 agonist)

The most exciting area is the availability of oral medications and those are likely coming around the next year or two, says Kushner

Walk into almost any Indian family gathering and high chances are someone will mention they are diabetic or have blood pressure issues or both before any meal is served

That recognition is richly deserved, since it is unclear if the GLP-1 drug path to obesity treatment, and all of the associated benefits, would have been seen at this time without her influence

But if you stick to smaller doses, it's unlikely to cause problems, says Dr

The cardioprotective effects of GLP-1 RAs along with their low risk of hypoglycemia make them preferred agents in any multidisciplinary approach for prevention of CVDs, reduction of the disease burden and improvement of prognosis