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Researchers also monitor tolerance or desensitization phenomena over time, as sustained agonism may reshape receptor trafficking
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Patients receiving the highest oral dose (14 mg daily) experienced average weight reductions of 10-15% of their starting body weight over 68 weeks of treatment
Although there has never been a clinical trial comparing these two approaches, a recent comprehensive meta-analysis showed no significant difference in mortality or clinical outcomes
For more in-depth information on these weight loss medications, read: Weight loss medications: Exploring the options
